5-Azacytidine
High-quality Bahan Kimia Organik supplied by Jinan Shenghe Chemical Co., Ltd. Competitive pricing, reliable delivery, and full technical support for B2B buyers worldwide.
Specifications
| Molecular Formula | C8H12N4O5 |
|---|---|
| Molecular Weight | 244.2047 |
| Melting Point | 228-230℃ |
| Boiling Point | 534.5°C at 760 mmHg |
| Flash Point | 277°C |
| Water Solubility | 0.5-1.0 g/100 mL at 21℃ |
| Vapor Pressure | 1.18E-13mmHg at 25°C |
Detailed Chemical Properties & Synonyms
Physical & Chemical Properties
本品为由微生物Streptoverticillium ladakanus所产生的嘧啶核苷类似物，也可用化学方法合成。是作用于S期的细胞周期特异性药，能迅速磷酸化并掺入RNA和DNA通过破坏核酸顺利翻译为蛋白质，而抑制蛋白质的合成。还可通过抑制乳清酸核苷酸脱羧酶而影响嘧啶的合成。
Applications / Uses
抗代谢药。主要适应症是对常规治疗无效的急性髓性白血病。亦用于乳腺癌、黑色素瘤、肠癌等。毒性主要表现为白细胞减少、血小板减少和贫血。恶心和呕吐为常见的不良反应，可通过长时间持续输注使症状改善，或在治病前24h至48h用止吐剂。其他毒性作用为腹泻、神经肌内障碍、发热、低血压和皮疹。制剂在用前3-4h新鲜配制。
Direct from the manufacturer. Jinan Shenghe Chemical Co., Ltd. supplies this product under ISO-controlled quality with full COA / MSDS / TDS documentation and flexible OEM packaging for global B2B buyers.
5-Azacytidine · CAS 320-67-2 · dibekalkan oleh Jinan Shenghe Chemical Co., Ltd.
Penerangan
5-Azacytidine · CAS 320-67-2 · C8H12N4O5. UNII HMS3373H14. LogP: -2.17.
Pengenalan
| CAS Nombor Pendaftaran | 320-67-2 |
|---|---|
| PubChem CID | 1805 |
| Formula molekul | C8H12N4O5 |
| IUPAC nama | 4-amino-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one |
| UNII (FDA) | HMS3373H14 |
Deskriptor Berkomputer
| Berat Molekul | 244.20 |
|---|---|
| XLogP3 | -2.2 |
| Kiraan Penderma Bon Hidrogen | 4 |
| Kiraan Penerima Bon Hidrogen | 5 |
| Kira Bon Boleh Putar | 2 |
| Jisim Tepat | 244.08076950 |
| Jisim Monoisotop | 244.08076950 |
| Kawasan Permukaan Kutub Topologi | 141 |
| Bilangan Atom Berat | 17 |
| Caj Rasmi | 0 |
Fizikal & Sifat Kimia
| LogP | -2.17 |
|---|
Sinonim
4-amino-1-pentofuranosyl-1,3,5-triazin-2(1h)-one; RefChem:1070226; DTXCID60209012; DTXSID20859335; Azacytidine, 5-; 5-AC; s-Triazin-2(1H)-one, 4-amino-1-.beta.-D-ribofuranosyl-; Azacitidine;5-AzaC;Ladakamycin; CCRIS93; NSC 281272; Kymarabine; Vidaza (Pharmion); Ara AC; WR-183027; Anitibiotic U 18496; 4-Amino-1-.beta.-D-ribofuranosyl-s-triazin-2(1H)-one; 4-amino-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one; Neuro_000048
Soalan Lazim
Apakah nombor CAS dan formula molekul bagi 5-Azacytidine?
CAS 320-67-2; formula molekul C8H12N4O5; berat molekul — g/mol.
Apakah nama lain yang 5-Azacytidine diketahui oleh?
4-amino-1-pentofuranosyl-1,3,5-triazin-2(1h)-one, RefChem:1070226, DTXCID60209012, DTXSID20859335, Azacytidine, 5-, 5-AC.
Apakah sifat fizikal utama bagi 5-Azacytidine?
LogP: -2.17.
Fakta di halaman ini diambil daripada PubChem (Perpustakaan Perubatan Negara AS) dan Wikidata. Data khusus gred — ujian, lembapan, saiz zarah, pembungkusan, jangka hayat — dikeluarkan setiap kelompok pada COA dan tidak diterbitkan di sini.
Aplikasi dan bidang penggunaan
5-Azacytidine (nombor CAS 320-67-2; formula C8H12N4O5; 244.20 g/mol) terutamanya digunakan dalam sintesis kimia, bahan kimia halus dan proses industri berkaitan. Spesifikasi, COA dan harga pukal 5-Azacytidine disediakan oleh pasukan jualan kami.
Produk serupa dalam kategori yang sama
Applications
抗代谢药。主要适应症是对常规治疗无效的急性髓性白血病。亦用于乳腺癌、黑色素瘤、肠癌等。毒性主要表现为白细胞减少、血小板减少和贫血。恶心和呕吐为常见的不良反应，可通过长时间持续输注使症状改善，或在治病前24h至48h用止吐剂。其他毒性作用为腹泻、神经肌内障碍、发热、低血压和皮疹。制剂在用前3-4h新鲜配制。
Packaging & Shipping
- Standard: 25 kg fiber drum / 200 kg steel drum with double PE liner
- Small pack: 1 kg / 5 kg aluminum foil bag for lab & sample
- Custom: packaging size and labeling per customer requirement
- Lead time: in-stock items ship within 3-5 business days
- Documents: COA, MSDS / SDS, TDS provided with every shipment
- Global: air, sea (FCL / LCL) and express to 80+ countries
Storage & Handling
Store in a cool, dry, well-ventilated place away from heat, direct sunlight and incompatible materials. Keep container tightly closed. Use appropriate personal protective equipment and refer to the SDS for full safety guidance before handling.
Frequently Asked Questions
Yes. A batch-specific COA and free or charged sample are available on request before bulk ordering.
Yes. We offer custom grade, particle size and purity adjustment based on your application and order volume.
MOQ depends on the product; small quantities are supported for R&D and trial runs.
Every batch is tested in-house and retains full traceability from raw material to finished goods.
Why Choose Jinan Shenghe Chemical
Request a Quote
Looking for pricing, availability or technical data for 5-Azacytidine?
Email us at sales@shenghechemical.com or use the button above. Our team typically responds within 1 business day.
About Jinan Shenghe Chemical Co., Ltd.
Jinan Shenghe Chemical Co., Ltd.
We are a professional chemical supplier based in Jinan, China. Since 2013, we have been connecting manufacturers and global B2B buyers with reliable sourcing, quality-controlled products and efficient logistics.
Our business covers food & feed additives, fine chemicals, pharmaceutical intermediates, eco-materials, coatings and specialty chemicals — all non-hazardous and compliant with our licensed scope.